One-Pot Cajun Chicken Alfredo

Featured in: One-Pot Comforts

This dish combines succulent diced chicken with orzo pasta, enveloped in a creamy, zesty Cajun Alfredo sauce. Cooked entirely in one pan for easy cleanup, it starts with searing the chicken, followed by sautéed onions and garlic, then toasting the orzo. Chicken broth and a blend of Cajun spices infuse the pasta as it simmers to al dente perfection. Cream and Parmesan enrich the sauce to a smooth, comforting finish. Garnished with fresh parsley, it delivers bold flavors that suit busy weeknights with minimal effort and maximum taste.

Updated on Sun, 23 Nov 2025 09:58:00 GMT
Creamy One-Pot Cajun Chicken Alfredo Orzo glistening in a skillet, ready to serve with fresh parsley. Save
Creamy One-Pot Cajun Chicken Alfredo Orzo glistening in a skillet, ready to serve with fresh parsley. | crumbnest.com

A quick and creamy one-pot meal that blends tender chicken, al dente orzo, and a zesty Cajun Alfredo sauce. Perfect for busy weeknights, this dish delivers bold flavors and comforting richness in just 30 minutes.

This dish has become a favorite on hectic evenings when I want something fast yet impressive. Everyone enjoys the creamy texture and the kick of Cajun spices without too much fuss.

Ingredients

  • Chicken: 1 lb (450 g) chicken breast, diced (substitute with shrimp or Andouille sausage if desired), Salt and black pepper, to taste
  • Spice Blend: 1 tbsp Cajun seasoning (adjust for spice preference), 1 tsp smoked paprika (regular paprika can be used), 1/4 tsp red pepper flakes (optional for extra heat)
  • Base: 2 tbsp olive oil, 2 tbsp butter, 1 medium onion, chopped (yellow or sweet preferred), 3 cloves garlic, minced
  • Pasta: 1 cup (190 g) orzo pasta (substitute with other small pasta if needed)
  • Sauce: 2 cups (480 ml) low sodium chicken broth, 1 cup (240 ml) heavy cream (or half and half for a lighter version), 1 cup (90 g) Parmesan cheese, freshly grated
  • Garnish: 1 tbsp fresh parsley, chopped

Instructions

Step 1:
Heat olive oil and butter in a large skillet over medium high heat. Add diced chicken, season with salt and pepper, and sear for 34 minutes until golden brown. Remove chicken and set aside.
Step 2:
In the same skillet, add chopped onion and sauté for 23 minutes until translucent. Stir in minced garlic and cook for 1 minute until fragrant.
Step 3:
Add orzo pasta to the skillet, stirring to combine. Toast for 12 minutes until lightly golden.
Step 4:
Pour in chicken broth and sprinkle in Cajun seasoning, smoked paprika, and red pepper flakes. Stir well, bring to a boil, then reduce heat to low. Cover and simmer for 1012 minutes, stirring occasionally, until orzo is al dente and most of the liquid is absorbed.
Step 5:
Remove skillet from heat. Gradually stir in heavy cream and Parmesan cheese until the sauce is creamy and smooth.
Step 6:
Return the cooked chicken to the skillet and stir to combine. Heat through for 1 minute. Taste and adjust seasoning as needed.
Step 7:
Garnish with fresh parsley before serving.
A steaming bowl of flavorful One-Pot Cajun Chicken Alfredo Orzo with tender chicken and Parmesan cheese. Save
A steaming bowl of flavorful One-Pot Cajun Chicken Alfredo Orzo with tender chicken and Parmesan cheese. | crumbnest.com

This recipe always brings my family together around the dinner table after a long day. Sharing this comforting meal fills our home with warmth and laughter.

Serving Suggestions

Serve with crusty bread or a green salad to balance out the richness of the sauce.

Variations

Add bell peppers or spinach to incorporate extra vegetables and color.

Nutritional Information

Per serving, this dish has approximately 560 calories, 28 g total fat, 45 g carbohydrates, and 35 g protein.

Golden orzo pasta combines with Cajun spices in this easy One-Pot Cajun Chicken Alfredo recipe. Save
Golden orzo pasta combines with Cajun spices in this easy One-Pot Cajun Chicken Alfredo recipe. | crumbnest.com

Enjoy this creamy, flavorful meal any night of the week with minimal effort and maximum satisfaction.

Recipe FAQ

Can I substitute the chicken with other proteins?

Yes, shrimp or Andouille sausage can replace chicken. Adjust cooking times accordingly to ensure proper doneness.

How spicy is the Cajun seasoning in this dish?

The spice level is moderate but can be adjusted by varying the amount of red pepper flakes and Cajun seasoning to taste.

Is it possible to make a lighter version of the dish?

Use half and half in place of heavy cream and reduce the Parmesan cheese for a lighter, less rich sauce.

What pasta alternatives work for this dish?

Small pastas similar to orzo, like acini di pepe or couscous, can be used as substitutes if desired.

Can I add vegetables to this dish?

Yes, adding bell peppers, spinach, or other vegetables adds color and nutrition without overpowering the flavors.

One-Pot Cajun Chicken Alfredo

Tender chicken and orzo meld with a rich Cajun Alfredo sauce in a quick one-pan meal.

Prep duration
10 min
Cook duration
20 min
Complete duration
30 min
Created by Chloe Martin


Skill Level Easy

Heritage Cajun

Output 4 Portions

Dietary considerations None specified

Components

Chicken

01 1 lb chicken breast, diced
02 Salt, to taste
03 Black pepper, to taste

Spice Blend

01 1 tbsp Cajun seasoning
02 1 tsp smoked paprika
03 1/4 tsp red pepper flakes (optional)

Base

01 2 tbsp olive oil
02 2 tbsp butter
03 1 medium onion, chopped
04 3 cloves garlic, minced

Pasta

01 1 cup orzo pasta

Sauce

01 2 cups low-sodium chicken broth
02 1 cup heavy cream
03 1 cup Parmesan cheese, freshly grated

Garnish

01 1 tbsp fresh parsley, chopped

Directions

Phase 01

Sear chicken: Heat olive oil and butter in a large skillet over medium-high heat. Season diced chicken with salt and black pepper. Sear chicken for 3 to 4 minutes until golden brown, then remove and set aside.

Phase 02

Sauté aromatics: In the same skillet, add chopped onion and cook for 2 to 3 minutes until translucent. Stir in minced garlic and cook for 1 minute until fragrant.

Phase 03

Toast orzo: Add orzo pasta to the skillet and stir to combine. Toast for 1 to 2 minutes until lightly golden.

Phase 04

Simmer with spices: Pour in chicken broth and add Cajun seasoning, smoked paprika, and red pepper flakes. Stir well, bring to a boil, then reduce heat to low. Cover and simmer for 10 to 12 minutes, stirring occasionally, until orzo is al dente and the liquid is mostly absorbed.

Phase 05

Incorporate cream and cheese: Remove skillet from heat. Gradually stir in heavy cream and Parmesan cheese until the sauce is creamy and smooth.

Phase 06

Combine chicken: Return the cooked chicken to the skillet and stir to combine. Heat through for 1 minute. Adjust seasoning as needed.

Phase 07

Garnish and serve: Sprinkle chopped fresh parsley on top before serving.

Tools needed

  • Large skillet with lid
  • Wooden spoon or spatula
  • Chef's knife
  • Cutting board
  • Measuring cups and spoons
  • Grater for Parmesan cheese

Allergy details

Review each component for potential allergens and seek medical guidance if you're uncertain about ingredients.
  • Contains dairy (butter, heavy cream, Parmesan cheese) and gluten (orzo pasta).

Nutritional information (each portion)

These values are approximate guides only and shouldn't replace professional medical consultation.
  • Energy: 560
  • Fats: 28 g
  • Carbohydrates: 45 g
  • Proteins: 35 g